|Total cases/person-years||>5 to 5 g/day|
|Overall||443/23,655||0.72 (0.53 to 0.98)|
|Energy limits: percentiles 5 to 95||403/21,681||0.78 (0.57 to 1.06)|
|Energy limits: percentiles 1 to 99||444/23,675||0.71 (0.53 to 0.96)|
|Excluding diabetics||227/11,653||0.96 (0.64 to 1.44)|
|Excluding participants older than 75||389/21,200||0.73 (0.56 to 1.25)|
|Excluding participants younger than 65||307/14,785||0.75 (0.52 to 1.06)|
|Depurating abstainers’ groupa||422/22,882||0.75 (0.55 to 1.02)|
|Including participants with prior depression at baseline||817/25,868||0.72 (0.57 to 0.90)|
|Updated alcohol intake assuming induction period: 1 to 2 yearsb||-||0.69 (0.50 to 0.96)|
|Updated alcohol intake assuming induction period: 2 to 3 yearsb||-||0.68 (0.47 to 1.00)|
aAfter excluding those participants who reported any alcohol intake throughout their life but not currently at baseline.
bRepeated-measurement analysis. Relative risks (95% confidence interval) for incident depression according to yearly updated measurements of alcohol intake. Considering incident cases during the last year of every two-year follow-up interval.
The PREDIMED Study 2003 to 2010.
All adjusted for age, sex, smoking, physical activity (MET-min/d), total energy intake (Kcal/day), baseline body mass index (kg/m2), marital status, intervention group, recruiting center, educational level, the number of persons living at home and alcohol intake at baseline.
Gea et al.
Gea et al. BMC Medicine 2013 11:192 doi:10.1186/1741-7015-11-192