Table 4

Sensitivity analyses
Total cases/person-years >5 to 5 g/day
Overall 443/23,655 0.72 (0.53 to 0.98)
Energy limits: percentiles 5 to 95 403/21,681 0.78 (0.57 to 1.06)
Energy limits: percentiles 1 to 99 444/23,675 0.71 (0.53 to 0.96)
Excluding diabetics 227/11,653 0.96 (0.64 to 1.44)
Excluding participants older than 75 389/21,200 0.73 (0.56 to 1.25)
Excluding participants younger than 65 307/14,785 0.75 (0.52 to 1.06)
Depurating abstainers’ groupa 422/22,882 0.75 (0.55 to 1.02)
Including participants with prior depression at baseline 817/25,868 0.72 (0.57 to 0.90)
Updated alcohol intake assuming induction period: 1 to 2 yearsb - 0.69 (0.50 to 0.96)
Updated alcohol intake assuming induction period: 2 to 3 yearsb - 0.68 (0.47 to 1.00)

aAfter excluding those participants who reported any alcohol intake throughout their life but not currently at baseline.

bRepeated-measurement analysis. Relative risks (95% confidence interval) for incident depression according to yearly updated measurements of alcohol intake. Considering incident cases during the last year of every two-year follow-up interval.

The PREDIMED Study 2003 to 2010.

All adjusted for age, sex, smoking, physical activity (MET-min/d), total energy intake (Kcal/day), baseline body mass index (kg/m2), marital status, intervention group, recruiting center, educational level, the number of persons living at home and alcohol intake at baseline.

Gea et al.

Gea et al. BMC Medicine 2013 11:192   doi:10.1186/1741-7015-11-192

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