Table 4 |
||
| Sensitivity analyses | ||
| Total cases/person-years | >5 to 5 g/day | |
| Overall | 443/23,655 | 0.72 (0.53 to 0.98) |
| Energy limits: percentiles 5 to 95 | 403/21,681 | 0.78 (0.57 to 1.06) |
| Energy limits: percentiles 1 to 99 | 444/23,675 | 0.71 (0.53 to 0.96) |
| Excluding diabetics | 227/11,653 | 0.96 (0.64 to 1.44) |
| Excluding participants older than 75 | 389/21,200 | 0.73 (0.56 to 1.25) |
| Excluding participants younger than 65 | 307/14,785 | 0.75 (0.52 to 1.06) |
| Depurating abstainers’ groupa | 422/22,882 | 0.75 (0.55 to 1.02) |
| Including participants with prior depression at baseline | 817/25,868 | 0.72 (0.57 to 0.90) |
| Updated alcohol intake assuming induction period: 1 to 2 yearsb | - | 0.69 (0.50 to 0.96) |
| Updated alcohol intake assuming induction period: 2 to 3 yearsb | - | 0.68 (0.47 to 1.00) |
aAfter excluding those participants who reported any alcohol intake throughout their life but not currently at baseline.
bRepeated-measurement analysis. Relative risks (95% confidence interval) for incident depression according to yearly updated measurements of alcohol intake. Considering incident cases during the last year of every two-year follow-up interval.
The PREDIMED Study 2003 to 2010.
All adjusted for age, sex, smoking, physical activity (MET-min/d), total energy intake (Kcal/day), baseline body mass index (kg/m2), marital status, intervention group, recruiting center, educational level, the number of persons living at home and alcohol intake at baseline.
Gea et al.
Gea et al. BMC Medicine 2013 11:192 doi:10.1186/1741-7015-11-192