Open Access Highly Accessed Research article

Alcohol intake, wine consumption and the development of depression: the PREDIMED study

Alfredo Gea1, Juan J Beunza2, Ramón Estruch34, Almudena Sánchez-Villegas35, Jordi Salas-Salvadó36, Pilar Buil-Cosiales7, Enrique Gómez-Gracia38, María-Isabel Covas39, Dolores Corella103, Miquel Fiol113, Fernando Arós123, José Lapetra133, Rosa-María Lamuela-Raventós143, Julia Wärnberg38, Xavier Pintó153, Lluis Serra-Majem35, Miguel A Martínez-González13* and for the PREDIMED GROUP

Author Affiliations

1 Department of Preventive Medicine and Public Health, Medical School-Clinica Universidad de Navarra, Pamplona, Spain

2 School of Medicine, Universidad Europea de Madrid, Madrid, Spain

3 CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain

4 Department of Internal Medicine, Hospital Clinic, University of Barcelona, Barcelona, Spain

5 Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain

6 Human Nutrition Unit, IISPV, Universitat Rovira i Virgili, Reus, Spain

7 Spain Primary Care, Servicio Navarro de Salud, Osasunbidea, Pamplona, Spain

8 Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Málaga, Málaga, Spain

9 Lipids and Cardiovascular Epidemiology Research Unit, Institut Municipal d’Investigació Mèdica (IMIM), Barcelona, Spain

10 Department of Preventive Medicine, University of Valencia, Valencia, Spain

11 Institute of Health Sciences (IUNICS), University of Balearic Islands, Palma de Mallorca, Spain

12 Department of Cardiology, Araba University Hospital, Vitoria, Spain

13 Department of Family Medicine, Primary Care Division of Sevilla, Centro de Salud San Pablo, Sevilla, Spain

14 Nutrition and Food Science Department– XaRTA, INSA, University of Barcelona, Barcelona, Spain

15 Internal Medicine Service, Hospital of Bellvitge, Hospitalet de Llobregat, Spain

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BMC Medicine 2013, 11:192  doi:10.1186/1741-7015-11-192

Published: 30 August 2013

Additional files

Additional file 1:

Flow chart of participants: the PREDIMED Study.

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Additional file 2:

Main analyses stratified by sex. Hazard ratios (95% confidence intervals) for incident depression according to categories of baseline daily alcohol intake, and Relative risks (95% confidence intervals) of incident depression according to categories of updated alcohol intake, using repeated measurements of diet during follow-up, stratified by sex. The PREDIMED Study 2003 to 2010.

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Additional file 3:

Fixed-effects models. Odds ratios (95% confidence intervals) for a new incident episode of depression, or recovery from an episode of depression, according to categories of baseline daily alcohol intake, using fixed-effects models. The PREDIMED Study 2003 to 2010.

Format: PDF Size: 59KB Download file

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Open Data