Table 6

Risk categorization results for six laboratory-based risk scores, each compared to non-laboratory-based risk score, mena
Dataset Number Fr_CVD_08 Fr_CVD_91 Fr_CHD_91 SCORE_h SCORE_l CUORE
Aggregate 5,751 89.8% 91.0% 86.4% 95.2% 95.6% 92.5%
BRISK 287 97.9% 97.2% 97.2% 99.3% 99.3% 97.9%
CRIBSA 357 93.3% 92.2% 91.6% 93.3% 93.8% 95.0%
Mangaung 276 90.5% 91.3% 85.5% 95.6% 95.6% 93.5%
QwaQwa 247 94.3% 94.3% 91.0% 97.6% 96.7% 95.9%
AHA-FS Urban 90 88.9% 91.1% 86.7% 93.3% 95.6% 95.6%
AHA-FS Rural 151 85.6% 84.9% 78.1% 94.5% 94.5% 90.4%
PURE, Urban 364 95.7% 95.7% 92.1% 97.6% 97.6% 97.0%
PURE, Rural 326 90.1% 90.7% 88.9% 95.1% 95.1% 90.7%
KwaZulu-Natal 130 87.6% 84.5% 81.4% 93.8% 92.2% 92.2%
CRISIC 382 96.9% 96.6% 94.8% 98.7% 99.0% 97.7%
Mamre 296 94.6% 93.2% 89.8% 96.6% 96.6% 95.3%
KORIS 2,571 90.9% 91.8% 88.0% 95.6% 96.0% 93.5%
Phoenix 274 92.7% 91.2% 86.1% 90.5% 90.5% 94.9%
Aggregateb 92.1% 93.0% 89.6% 95.5% 95.9% 94.2%

a‘Agreement’ based on dichotomous risk categorization corresponding to 10-year Framingham (2008) CVD risk >20%, unless otherwise noted. For SCORE this is equivalent to a 5% fatal CVD risk; bthreshold of 10-year Framingham CHD risk >20%. CHD coronary heart disease, CVD cardiovascular disease, Fr Framingham.

Gaziano et al.

Gaziano et al. BMC Medicine 2013 11:170   doi:10.1186/1741-7015-11-170

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