|Study populations, inputs, and outcomes used to construct each of the risk scores used in this study|
|Non-laboratory-based (Gaziano et al., 2008) ||NHANES I (US, 1971 to 1975)||Age, sex, smoking, diabetes, systolic blood pressure, treatment for hypertension, BMI||CVD death, MI, stroke, CHF, coronary bypass, PTCA|
|Framingham CVD 2008 (D’Agostino et al., 2008) ||Framingham, MA, US (1968 to 1987)||Age, sex, smoking, diabetes, systolic blood pressure, treatment for hypertension, total cholesterol, HDL cholesterol||MI, angina, coronary insufficiency, CHD death, stroke, TIA, CHF, PVD, CVD death|
|Framingham CVD (Anderson et al., 1991) ||Framingham, MA, (US., 1968 to 1975)||Age, sex, smoking, diabetes, systolic blood pressure, total cholesterol, HDL cholesterol||Same as above|
|Framingham CHD (Anderson et al., 1991) ||Same as above||Same as above||MI, CHD death, angina, coronary insufficiency|
|SCORE, high risk (Conroy et al., 2003) ||High risk European countriesb||Age, sex, smoking, systolic blood pressure, total cholesterol||Death from: hypertensive disease, IHD, cerebrovascular disease|
|SCORE, low risk (Conroy et al., 2003) ||Low risk European countriesc||Same as above||Same as above|
|CUORE (Giampaoli et al., 2007) ||Italy (1983 to 1997)||Age, sex, smoking, diabetes, systolic blood pressure, treatment for hypertension, total cholesterol, HDL cholesterol||Fatal and non-fatal MI or stroke|
aYears indicate when baseline values were collected; bapplicable for all non-low risk European countries; capplicable for Belgium, France, Greece, Italy, Luxembourg, Portugal, Spain, and Switzerland. BMI, body-mass index; CHD coronary heart disease, CHF congestive heart failure, CVD cardiovascular disease, HDL high-density lipoprotein, IHD ischemic heart disease, MI myocardial infarction, NHANES National Health and Nutrition Examination Survey, PTCA percutaneous transluminal coronary angioplasty, PVD peripheral vascular disease, TIA transient ischemic attack.
Gaziano et al.
Gaziano et al. BMC Medicine 2013 11:170 doi:10.1186/1741-7015-11-170