Pharmacological treatments in ARDS; a state-of-the-art update
1 Centre for Infection and Immunity, Health Sciences Building, Queen’s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK
2 Regional Intensive Care Unit, Royal Victoria Hospital, 274 Grosvenor Road, Belfast BT12 6BA, UK
BMC Medicine 2013, 11:166 doi:10.1186/1741-7015-11-166Published: 20 August 2013
Despite its high incidence and devastating outcomes, acute respiratory distress syndrome (ARDS) has no specific treatment, with effective therapy currently limited to minimizing potentially harmful ventilation and avoiding a positive fluid balance. Many pharmacological therapies have been investigated with limited success to date. In this review article we provide a state-of-the-art update on recent and ongoing trials, as well as reviewing promising future pharmacological therapies in ARDS.