Email updates

Keep up to date with the latest news and content from BMC Medicine and BioMed Central.

Journal App

google play app store
Open Access Highly Accessed Review

Pharmacological treatments in ARDS; a state-of-the-art update

Andrew James Boyle12, Rob Mac Sweeney2 and Daniel Francis McAuley12*

Author Affiliations

1 Centre for Infection and Immunity, Health Sciences Building, Queen’s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK

2 Regional Intensive Care Unit, Royal Victoria Hospital, 274 Grosvenor Road, Belfast BT12 6BA, UK

For all author emails, please log on.

BMC Medicine 2013, 11:166  doi:10.1186/1741-7015-11-166

Published: 20 August 2013

Abstract

Despite its high incidence and devastating outcomes, acute respiratory distress syndrome (ARDS) has no specific treatment, with effective therapy currently limited to minimizing potentially harmful ventilation and avoiding a positive fluid balance. Many pharmacological therapies have been investigated with limited success to date. In this review article we provide a state-of-the-art update on recent and ongoing trials, as well as reviewing promising future pharmacological therapies in ARDS.

Keywords:
Acute lung injury; Acute respiratory distress syndrome