Anti-inflammatory effects of stem cell educator therapy. (A) Up-regulation of plasma levels of TGF-β1 in T2D patients at baseline and four weeks after Stem Cell Educator therapy. (B) Flow analysis of intra-cellular cytokines demonstrating differential effects on key interleukins at four weeks post-treatment. (C) Down-regulation percentage of CD86+CD14+monocytes in T2D patients at baseline and four weeks after Stem Cell Educator therapy. (D) Flow Analysis of CD4+CD25+Foxp3+ Tregs demonstrating no change in the percentage of Tregs at four weeks post-treatment.
Zhao et al. BMC Medicine 2013 11:160 doi:10.1186/1741-7015-11-160