Figure 2.

The androgen specific cell differentiation is dependent on testosterone uptake, its intracellular metabolism and the specificity of the androgen-androgen receptor (AR) complex in concert with coregulators in transcriptional control. CoR, coregulators; GTF, general transcription factors; HRE, hormone response elements; HSP, heat shock proteins; P, phosphorylation sites.

Hiort BMC Medicine 2013 11:152   doi:10.1186/1741-7015-11-152
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