Table 1

Meta-analyses examining the association between depression and incidence of mortality or morbidity in disease-free subjects
Incident event Reference Nr studies included Nr subjects included Pooled risk (95% CI) of depression
Overall mortality Cuijpers et al.[5] 25 106,628 1.81 (1.58 to 2.07)
Heart disease Nicholson et al. [3] 21 124,509 1.81 (1.53 to 2.15)
Hypertension Meng et al. [12] 9 22,367 1.42 (1.09 to 1.86)
Stroke Dong et al. [13] 17 206,641 1.34 (1.17 to 1.54)
Diabetes Mezuk et al. [4] 13 212,019 1.60 (1.37 to 1.88)
Alzheimer’s disease Gao et al. [14] 4 5,656 1.66 (1.29 to 2.14)
Obesity (BMI ≥30) Luppino et al. [15] 9 6,436 1.58 (1.33 to 1.81)
Cancer Chida et al. [16] 25 n.a. 1.29 (1.14 to 1.46)

BMI, Body mass index; CI, Confidence interval; n.a., Not available.

Penninx et al.

Penninx et al. BMC Medicine 2013 11:129   doi:10.1186/1741-7015-11-129

Open Data