Table 2 |
||||
| Research domain criteria, October 2012 (constructs are listed within each domain) | ||||
| Negative valence domain | Positive valence systems | Cognitive systems | Systems for social processes | Arousal/modulatory systems |
| Acute threat (‘fear’) | Approach motivation | Attention | Affiliation and attachment | Arousal |
| Potential threat (‘anxiety’) | Initial responsiveness to reward | Perception | Social communication | Biological rhythms |
| Sustained threat | Sustained responsiveness to reward | Working memory | Perception and understanding of self | Sleep-wake |
| Loss | Reward learning | Declarative memory | Perception and understanding of others | |
| Frustrative nonreward | Habit | Language behavior | ||
| Cognitive (effortful) control | ||||
Cuthbert and Insel
Cuthbert and Insel BMC Medicine 2013 11:126 doi:10.1186/1741-7015-11-126
