Phenotypic discordance upon paternal or maternal transmission. Rats of the F1 generation were mated to cross fathers weaned on d16 (dark lines) or d26 with mothers weaned on d21 (A, C, E), and mothers weaned on d16 (dark lines) or d26 with fathers weaned on d21 (B, D, F): F2 Offspring were measured for crown-tale length (cm; A, B), weight to give the BMI (g/cm2; C, D), testicular volume (ml; E, F) and vaginal opening (day; solid bars) and first estrous (day; gray bars) (G). Statistically significant differences between d16 and d26 rats are indicated by ($) for P <0.04, (*) for P <0.01, (&) for P <0.001 with a two-way t-test. Mean ± SEM, n = 12 per group.
Crispel et al. BMC Medicine 2013 11:114 doi:10.1186/1741-7015-11-114