Table 2

Age-adjusted (model I) and fully-adjusted (model II) odds ratios for medical comorbidities in men with lifetime history of mood and anxiety disorders
Mood disorders Anxiety disorders
Model Odds ratio 95% CI P value Odds ratio 95% CI P value
Musculoskeletal disease I 1.43 (0.93 to 2.21) 0.104 1.39 (0.72 to 2.71) 0.328
II 1.47 (0.94 to 2.31) 0.092 1.70 (0.85 to 3.43) 0.135
Thyroid disorders I 1.64 (0.52 to 5.12) 0.396 5.29 (1.63 to 7.14) 0.005
II 1.81 (0.56 to 5.83) 0.321 5.54 (1.64 to 18.64) 0.006
Metabolic risk factors I 1.30 (0.85 to 1.99) 0.234 1.92 (0.96 to 3.83) 0.066
IIa 1.29 (0.83 to 2.00) 0.265 2.20 (1.07 to 4.53) 0.032
GORD I 2.41 (1.48 to 3.00) <0.001 3.84 (2.01 to 7.33) <0.001
II 2.67 (1.60 to 4.47) <0.001 4.25 (2.18 to 8.26) <0.001
Gastrointestinal disorders I 1.47 (0.93 to 2.30) 0.096 2.22 (1.20 to 4.10) 0.011
II 1.46 (0.91 to 2.34) 0.112 2.40 (1.28 to 4.50) 0.006
Recurrent headaches I 2.46 (1.29 to 4.69) 0.007 0.63 (0.15 to 2.69) 0.537
II 2.53 (1.30 to 4.96) 0.007 0.67 (0.16 to 2.89) 0.592
Syncope and seizures I 2.01 (1.31 to 3.09) 0.002 1.46 (0.75 to 2.85) 0.263
II 2.01 (1.28 to 3.16) 0.002 1.55 (0.78 to 3.07) 0.207
Cardiovascular disease I 1.27 (0.82 to 1.93) 0.292 1.93 (0.60 to 2.13) 0.708
II 1.28 (0.82 to 2.01) 0.276 1.15 (0.59 to 2.25) 0.678
Pulmonary disease All I - - - 0.95 (0.48 to 1.86) 0.874
II - - - 1.02 (0.51 to 2.03) 0.956
<60 years old I 0.90 (0.52 to 1.58) 0.725 - - -
II 1.01 (0.57 to 1.79) 0.971 - - -
≥60 years old I 2.75 (1.45 to 5.21) 0.002 - - -
II 2.65 (1.34 to 5.21) 0.005 - - -
Liver disorders I 2.64 (1.40 to 4.98) 0.003 0.97 (0.29 to 3.24) 0.964
II 3.03 (1.57 to 5.83) 0.001 1.03 (0.30 to 3.46) 0.967
Cancer I 0.95 (0.56 to 1.61) 0.839 1.03 (0.47 to 2.29) 0.933
II 0.90 (0.52 to 1.56) 0.706 1.03 (0.46 to 2.32) 0.938
Psoriasis I 1.63 (0.75 to 3.55) 0.219 2.44 (0.91 to 6.57) 0.076
II 1.41 (0.51 to 2.91) 0.648 2.77 (1.00 to 7.67) 0.049
High medical burden I 1.80 (1.16 to 2.77) 0.008 2.82 (1.43 to 5.53) 0.003
IIa 1.86 (1.19 to 2.91) 0.007 3.23 (1.61 to6.47) 0.001

aModel not adjusted for BMI as it is recorded in the medical condition. Model I – Age-adjusted; Model II – Fully-adjusted including: age, BMI, SES, physical activity, smoking and alcohol consumption. BMI, body mass index; CI, confidence interval; GORD, gastro oesaphogeal reflux disease; SES, socioeconomic status.

Sanna et al.

Sanna et al. BMC Medicine 2013 11:110   doi:10.1186/1741-7015-11-110

Open Data