Table 2

Different theories about etiopathogenesis of calcific tendinopathy (CT).

Type

Cause

Reference(s) by first author

Year(s)


Degenerative calcification

Vascular ischemia

Sandstrom [12]

1938

Repetitive trauma

Bishop [13] and Bosworth [14]

1939, 1941

Necrosis of tenocytes and intracellular calcium accumulation

Mohr [17]

1990

Reactive calcification

Active cell mediated process

Uhthoff [27]

1997

Endochondral ossification

Endochondral ossification of fibrocartilage at the enthesis of the tendon

Benjamin [34]

2000

Chondral metaplasia

Erroneous differentiation of tendon-derived stem cells (TDSCs)

Rui [46]

2011


Oliva et al. BMC Medicine 2012 10:95   doi:10.1186/1741-7015-10-95

Open Data