Implications of stress-induced genetic variation for minimizing multidrug resistance in bacteria
Department of Molecular Biology and Ecology of Plants, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel
BMC Medicine 2012, 10:89 doi:10.1186/1741-7015-10-89Published: 13 August 2012
Additional file 1:
Proofs and additional figures and tables. Additional file 1 contains proofs for all the equations presented in the main text. It also contains two additional figures presenting the relative efficiency of inhibiting double resistance emergence for the mixing and cycling strategies (Figures S1 and S2), and a table comparing the mean frequency of overall infected patients, taken over various parameter sets, for all three strategies (Table S1).
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