Table 2 |
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|
Primary and secondary outcomes with group differences for change after treatment |
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|
Treatment group (n = 33) |
Control group (n = 31) |
Between-group differencea |
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|
|
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|
Baseline (n = 33) |
Week 6 (n = 31) |
Baseline (n = 31) |
Week 6 (n = 29) |
Diff. |
95% CI |
P value |
|
|
|
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|
Primary outcomes |
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|
SPB, mmHg |
148.5 ± 12.3 |
130.5 ± 11.9 |
144.7 ± 14.4 |
143.8 ± 11.9 |
-16.5 |
-20.6 to 12.3 |
< 0.001 |
|
HOMA index |
4.8 ± 7.2 |
3.6 ± 2.7 |
4.5 ± 3.8 |
4.1 ± 3.6 |
-0.7 |
-2.1 to 0.6 |
0.28 |
|
Secondary outcomes |
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|
Glucose, mg/dl |
110.7 ± 29.4 |
98.5 ± 24.0 |
109.1 ± 34.4 |
107.3 ± 33.6 |
-13.3 |
-18.8 to -8.1 |
< 0.001 |
|
HbA1c, % |
5.56 ± 0.61 |
5.36 ± 0.58 |
5.84 ± 1.24 |
5.72 ± 1.24 |
-0.19 |
-0.29 to -0.08 |
< 0.001 |
|
Insulin, μU/ml |
15.4 ± 17.7 |
14.2 ± 8.9 |
16.7 ± 12.7 |
15.2 ± 11.6 |
-1.2 |
-5.4 to 3.0 |
0.580 |
|
Adiponectin, μg/ml |
9.15 ± 3.40 |
9.83 ± 5.00 |
8.75 ± 4.00 |
9.40 ± 4.40 |
0.24 |
-0.90 to 1.39 |
0.68 |
|
hs-CRP, mg/dl |
0.32 ± 0.44 |
0.33 ± 0.39 |
0.30 ± 0.37 |
0.31 ± 0.38 |
0.01 |
-0.05 to 0.07 |
0.80 |
|
DBP, mmHg |
93.2 ± 6.8 |
83.7 ± 5.7 |
90.8 ± 6.6 |
90.0 ± 8.6 |
-8.2 |
-10.7 to -5.7 |
< 0.001 |
|
Heart rate, beats/min |
72.1 ± 8.2 |
70.0 ± 5.8 |
74.2 ± 9.5 |
76.2 ± 8.4 |
-5.7 |
-8.1 to -3.2) |
< 0.001 |
|
Ferritin, ng/ml |
188.3 ± 212.4 |
104.6 ± 132.5 |
173.2 ± 132.9 |
149.4 ± 124.9* |
-74.2 |
101.6 to -46.8 |
< 0.001 |
|
Iron, ng/ml |
100.6 ± 34.2 |
75.8 ± 28.5 |
100.8 ± 26.2 |
102.8 ± 36.9* |
-27.1 |
-41.1 to -13.2 |
< 0.001 |
|
Triglycerides, mg/dl |
154.0 ± 66.7 |
158.0 ± 64.7 |
204.6 ± 120.0 |
178. ± 70.7* |
-2.9 |
-31.4 to 25.6 |
0.84 |
|
Cholesterol, mg/dl |
208.4 ± 36.5 |
212.2 ± 38.6 |
211.0 ± 37.7 |
206.4 ± 36.4* |
3.1 |
-6.7 to 12.8 |
0.54 |
|
HDL-C, mg/dl |
55.9 ± 15.0 |
58.9 ± 17.9 |
54.2 ± 16.5 |
55.0 ± 16.1* |
3.0 |
-0.3 to 6.3 |
0.07 |
|
LDL-C, mg/dl |
131.2 ± 35.8 |
123.5 ± 35.9 |
130.7 ± 32.8 |
125.1 ± 29.1* |
-4.9 |
-11.8 to 2.0 |
0.16 |
|
LDL/HDL ratio |
2.48 ± 0.88 |
2.21 ± 0.80 |
2.56 ± 0.82 |
2.43 ± 0.82 |
-0.23 |
-0.38 to -0.08 |
< 0.01 |
|
|
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|
Abbreviations: DBP, diastolic blood pressure; HDL-C, HDL cholesterol; hs-CRP, high-sensitivity C-reactive protein; HOMA, homeostasis model assessment; LDL-C, LDL cholesterol; SBP, Systolic Blood Pressure: adjusted. aMean values ± SD at baseline and after 6 weeks and mean difference (95% confidence interval). |
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|
Houschyar et al. BMC Medicine 2012 10:54 doi:10.1186/1741-7015-10-54 |
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