Table 2

Primary and secondary outcomes with group differences for change after treatment

Treatment group (n = 33)

Control group (n = 31)

Between-group differencea


Baseline

(n = 33)

Week 6

(n = 31)

Baseline

(n = 31)

Week 6

(n = 29)

Diff.

95% CI

P value


Primary outcomes

SPB, mmHg

148.5 ± 12.3

130.5 ± 11.9

144.7 ± 14.4

143.8 ± 11.9

-16.5

-20.6 to 12.3

< 0.001

HOMA index

4.8 ± 7.2

3.6 ± 2.7

4.5 ± 3.8

4.1 ± 3.6

-0.7

-2.1 to 0.6

0.28

Secondary outcomes

Glucose, mg/dl

110.7 ± 29.4

98.5 ± 24.0

109.1 ± 34.4

107.3 ± 33.6

-13.3

-18.8 to -8.1

< 0.001

HbA1c, %

5.56 ± 0.61

5.36 ± 0.58

5.84 ± 1.24

5.72 ± 1.24

-0.19

-0.29 to -0.08

< 0.001

Insulin, μU/ml

15.4 ± 17.7

14.2 ± 8.9

16.7 ± 12.7

15.2 ± 11.6

-1.2

-5.4 to 3.0

0.580

Adiponectin, μg/ml

9.15 ± 3.40

9.83 ± 5.00

8.75 ± 4.00

9.40 ± 4.40

0.24

-0.90 to 1.39

0.68

hs-CRP, mg/dl

0.32 ± 0.44

0.33 ± 0.39

0.30 ± 0.37

0.31 ± 0.38

0.01

-0.05 to 0.07

0.80

DBP, mmHg

93.2 ± 6.8

83.7 ± 5.7

90.8 ± 6.6

90.0 ± 8.6

-8.2

-10.7 to -5.7

< 0.001

Heart rate, beats/min

72.1 ± 8.2

70.0 ± 5.8

74.2 ± 9.5

76.2 ± 8.4

-5.7

-8.1 to -3.2)

< 0.001

Ferritin, ng/ml

188.3 ± 212.4

104.6 ± 132.5

173.2 ± 132.9

149.4 ± 124.9*

-74.2

101.6 to -46.8

< 0.001

Iron, ng/ml

100.6 ± 34.2

75.8 ± 28.5

100.8 ± 26.2

102.8 ± 36.9*

-27.1

-41.1 to -13.2

< 0.001

Triglycerides, mg/dl

154.0 ± 66.7

158.0 ± 64.7

204.6 ± 120.0

178. ± 70.7*

-2.9

-31.4 to 25.6

0.84

Cholesterol, mg/dl

208.4 ± 36.5

212.2 ± 38.6

211.0 ± 37.7

206.4 ± 36.4*

3.1

-6.7 to 12.8

0.54

HDL-C, mg/dl

55.9 ± 15.0

58.9 ± 17.9

54.2 ± 16.5

55.0 ± 16.1*

3.0

-0.3 to 6.3

0.07

LDL-C, mg/dl

131.2 ± 35.8

123.5 ± 35.9

130.7 ± 32.8

125.1 ± 29.1*

-4.9

-11.8 to 2.0

0.16

LDL/HDL ratio

2.48 ± 0.88

2.21 ± 0.80

2.56 ± 0.82

2.43 ± 0.82

-0.23

-0.38 to -0.08

< 0.01


Abbreviations: DBP, diastolic blood pressure; HDL-C, HDL cholesterol; hs-CRP, high-sensitivity C-reactive protein; HOMA, homeostasis model assessment; LDL-C, LDL cholesterol; SBP, Systolic Blood Pressure: adjusted.

aMean values ± SD at baseline and after 6 weeks and mean difference (95% confidence interval).

Houschyar et al. BMC Medicine 2012 10:54   doi:10.1186/1741-7015-10-54

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