Table 8

Univariable analyses of relation of UBE2C protein and standard variables to overall survival in 92 women with node-positive breast cancer [183].

Variable

HR

95% CI

P


Age

1.06

1.01 to 1.12

0.026

Histology (IDC versus others)

0.48

0.18 to 1.27

0.139

Histological size (<20 mm versus ≥20 mm)

2.97

0.68 to 12.94

0.147

SBR (I versus II versus III)

3.97

1.67 to 9.47

0.001

Positive nodes (1 versus 2 versus 3 versus >3)

1.81

1.19 to 274

0.005

Estrogen receptor (+versus -)

0.18

0.07 to 0.47

<0.001

Progesterone receptor (+versus -)

0.51

0.19 to 1.37

0.182

IHC Ki-67 (<11% versus ≥11%)

8.59

1.14 to 64.57

0.037

IHC UBE2C (<11% versus ≥11%)

7.14

1.64 to 31.11

0.009

NPI scores (1 versus 2 versus 3)

4.48

1.74 to 11.52

0.002


CI: confidence interval; IDC: infiltrating ductal carcinoma; IHC: immunohistochemistry; HR: hazard ratio; NPI: Nottingham Prognostic Index; SBR: Scarff-Bloom-Richardson.

Altman et al. BMC Medicine 2012 10:51   doi:10.1186/1741-7015-10-51

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