Table 2 

Correlation between FSSG scores and 20 background factors of the 19,864 participants (multivariate analysis). 

Factors 
Regression coefficient 
Pvalue 
Standardized regression coefficient (β) 


Inadequate sleep (†) 
1.678 
< 0.0001 * 
0.1576 
Use of other digestive drugs 
2.497 
< 0.0001 * 
0.1038 
Use of PPIs 
3.749 
< 0.0001 * 
0.0972 
Use of H_{2}RAs 
2.900 
< 0.0001 * 
0.0903 
Increased body weight in adulthood 
0.878 
< 0.0001 * 
0.0814 
Dinner just before bedtime (†) 
0.695 
< 0.0001 * 
0.0612 
Habit of midnight snack (†) 
0.788 
< 0.0001 * 
0.0554 
BMI 
0.084 
< 0.0001 * 
0.0535 
Use of NSAIDs 
1.179 
< 0.0001 * 
0.0512 
Gender (female) 
0.509 
< 0.0001 * 
0.0481 
Frequent lack of breakfast (†) 
0.683 
< 0.0001 * 
0.0449 
Lack of habitual physical exercise (†) 
0.424 
< 0.0001 * 
0.0350 
Age 
0.018 
< 0.0001 * 
0.0333 
Use of antihyperglycemic agents 
0.813 
0.0002 * 
0.0258 
Habit of quick eating (†) 
0.273 
0.0002 * 
0.0255 
Habit of alcohol drinking (†) 
0.278 
0.0006 * 
0.0250 
History of gastrectomy 
1.232 
0.0004 * 
0.0241 
History of cardiovascular disease 
0.637 
0.0033 * 
0.0201 
Habit of smoking (†) 
0.240 
0.0100 * 
0.0184 
Use of steroids 
0.303 
0.3756 
0.0060 


BMI, body mass index; H_{2}RAs, histamine H_{2}receptor antagonists; NSAIDs, nonsteroidal antiinflammatory drugs; PPIs, proton pump inhibitors. Multiple regression analysis was performed focusing on the 20 background factors, comprised of two continuous variables (age and BMI) and other 18 categorical variables. The level of significance in each factor was set at Pvalue < 0.05 (*). All the 20 background factors were sorted in order of absolute values of standardized regression coefficients. Eight lifestylerelated factors are denoted with (†). 

Yamamichi et al. BMC Medicine 2012 10:45 doi:10.1186/174170151045 