Table 6

List of prostate-specific proteins which have not been previously studied as serum cancer or benign disease biomarkers

Gene

Protein name

Proteome identified in:

CM proteome from prostate cancer cell lines

Seminal plasma proteome[25]

Non-prostate proteome

NPY

Neuropeptide Y

√ VCaPa

PSCA

Prostate stem cell antigen

√ PC3 [28]

√ Normal and cancer pancreatic tissueb; CM proteome from pancreatic cancer cell lines SU.86.86, CAPAN1 [33]

RLN1

Relaxin 1

SLC45A3

Solute carrier family 45, member 3


aCM proteome from prostate cancer cell line (P Saraon et al., unpublished work); bproteome of normal and cancer pancreatic tissue (H Kosanam et al., unpublished work). CM: conditioned media.

Prassas et al. BMC Medicine 2012 10:39   doi:10.1186/1741-7015-10-39

Open Data