Table 2

Forty-eight proteins identified as tissue-specific, strongly expressed and secreted or shed in colon, lung, pancreatic or prostate tissuea

Tissue

Gene

BioGPS [15,16]

C-It [9]

HPA [20]

TiGER [11]

UniGene [13]

VeryGene [18]

Previously studied as a (tissue) cancer or benign disease serum biomarker [reference]


Colon

CEACAM7

CLCA1

GPA33

LEFTY1

ZG16

Lung

IRX5

LAMP3

MFAP4

SCGB1A1

SFTPA2

[54-56]

SFTPB

[55]

SFTPC

SFTPD

[56]

TMEM100

Pancreas

AQP8

CEL

[60]

CELA2A

[61]

CELA2B

CELA3B

CPA1

[62]

CPA2

[62]

CPB1

[63]

CTRB1

CTRB2

CTRC

CUZD1

GCG

IAPP

INS

KLK1

PNLIP

[64]

PNLIPRP1

PNLIPRP2

PPY

PRSS1

[65]

PRSS3

REG1B

REG3G

SLC30A8

SYCN

[33]

Prostate

ACPP

[66]

FOLH1

[67]

KLK2

[68]

KLK3

[66]

NPY

PSCA

RLN1

SLC45A3


aTissue-specific proteins as it applies to this table indicates protein expression was manually verified in BioGPS and/or HPA databases. HPA: Human Protein Atlas; TiGER: Tissue-specific and Gene Expression and Regulation.

Prassas et al. BMC Medicine 2012 10:39   doi:10.1186/1741-7015-10-39

Open Data