Effect of adding an EGFR siRNA to afatinib on cell growth inhibition. Lung cancer cells were treated with afatinib as mentioned in Figure 5. *P < 0.05 and **P < 0.01 compared to controls with only siRNA transfection. "black triangle" P < 0.05 and "double black triangles" P < 0.01 compared to agents plus control siRNA.
Chen et al. BMC Medicine 2012 10:28 doi:10.1186/1741-7015-10-28