Table 2

Tumor-generation assay using injection of 500, 1,000 or 5,000 G0 cellsa, b.

Tumor generation, n/total n

Mean time to tumor generation, days


cell injection

5,000c

1,000c

500c

5,000

1,000

500


G0

5/5

5/5

3/5

25.4

26.6

27.6

Non-G0

2/5

1/5

0/5

22

21

--


a, b

aExperiments were repeated three times with similar results; this table presents the result of one experiment.

bG0 cells were isolated using Hoechst-Pyronin Y-based fluorescence-activated cell sorting.

cThe t-test was carried out to determine the difference between the two groups in three experiments: cP < 0.01.

Sun et al. BMC Medicine 2012 10:172   doi:10.1186/1741-7015-10-172

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