Table 3

Lesion statistics from serial fluid-attenuated inversion recovery (FLAIR) imaging

Comparisons

No. of new lesions

No. of subjects

t Test

P value


t1 to t2

-0.08 (0.82)

12

-0.35

0.732

t2 to t3

-0.36 (0.64)

11

-1.90

0.087

t3 to t4

0.17 (0.52)

6

0.79

0.465

Volume change of lesions

t1 to t2

54.9 (247.4)

12

0.77

0.458

t2 to t3

38.3 (116.9)

11

1.09

0.302

t3 to t4

-100.42 (237.7)

6

-1.03

0.348


t1 = timepoint 1, start of the race; t2 = timepoint 2, after an average distance of 2,326 km; t3 = timepoint 3, after an average distance of 4,005 km from t1; t4 = timepoint 4, follow-up measurements around 8 months after finishing the race. No. of new lesions = across participants averaged number of new lesions (SD) observed between two consecutive timepoints. No. of subjects = number of subjects with two consecutive FLAIR measurements to enter a paired t test. Volume change of lesions = for calculation of lesion volumes see Methods section, shown is the difference between averaged sums of lesion volumes obtained at two consecutive timepoints, units are mm3.

Freund et al. BMC Medicine 2012 10:170   doi:10.1186/1741-7015-10-170

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