Open Access Research article

Substantial and reversible brain gray matter reduction but no acute brain lesions in ultramarathon runners: experience from the TransEurope-FootRace Project

Wolfgang Freund1*, Sonja Faust1, Frank Birklein2, Christian Gaser3, Arthur P Wunderlich1, Marguerite Müller1, Christian Billich1, Markus S Juchems1, Bernd L Schmitz5, Georg Grön4 and Uwe H Schütz16

Author Affiliations

1 Department of Diagnostic and Interventional Radiology, University Hospitals Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany

2 Department of Neurology, University Medical Centre Mainz, Langenbeckstraße 1/503, 55131 Mainz, Germany

3 Departments of Psychiatry and Neurology, Jena University Hospital, Jahnstraße 3, 07743 Jena, Germany

4 Section Neuropsychology and Functional Imaging, University Hospitals Ulm, Leimgrubenweg 12-14, 89073 Ulm, Germany

5 Section Neuroradiology, University Hospitals Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany

6 Outpatient Rehabilitation Centre at University Hospitals Ulm, Pfarrer-Weiß-Weg 10, 89077 Ulm, Germany

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BMC Medicine 2012, 10:170  doi:10.1186/1741-7015-10-170


See related commentary http://www.biomedcentral.com/1741-7015/10/171

Published: 21 December 2012

Additional files

Additional file 1:

Tables S1-3. Table S1: Fluid-attenuated inversion recovery (FLAIR) imaging of brain lesions. Observations from timepoint 1 (t1) to t2; only subjects with two consecutive measurements. The table contains single subject data for FLAIR lesion comparisons between timepoints 1 to 2. Table S2: FLAIR imaging of brain lesions. Observations from t2 to t3; only subjects with two consecutive measurements. The table contains single subject data for FLAIR lesion comparisons between timepoints 2 to 3. Table S3: FLAIR imaging of brain lesions. Observations from t3 to t4; only subjects with two consecutive measurements. The table contains single subject data for FLAIR lesion comparisons between timepoints 3 to 4.

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