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Open Access Research article

Validation of a model to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD: the rotterdam ischemic heart disease and stroke computer simulation (RISC) model

Bob JH van Kempen, Bart S Ferket, Albert Hofman, Ewout W Steyerberg, Ersen B Colkesen, S Matthijs Boekholdt, Nicholas J Wareham, Kay-Tee Khaw and MG Myriam Hunink*

BMC Medicine 2012, 10:158  doi:10.1186/1741-7015-10-158

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