Table 1

Description of the thirteen breast cancer screening guidelines included in the study.

Guidelines (organization), year

Evidence base

Syndromes considered

Target population

Risk assessment

Criteria for genetic risk evaluation

Diagnosis and counselling

Treatment


Breast Cancer Screening and Diagnosis (National Cancer Comprehensive Network), 20101 [2]

Yes

BRCA1/2, CS, LFS

General population

Yes

Yes

Yes

Yes

Health Screening, MOH Clinical Practice Guidelines (Ministry of Health, Singapore), 20102 [15]

Yes

BRCA1/2

General population

No

No

No

Yes

Hereditary Breast and Ovarian Cancer Syndrome (American College of Obstetricians and Gynecologists), 20091 [16]

No

BRCA1/2

General population

Yes

Yes

Yes

Yes

Diagnosis of Breast Disease (Institute for Clinical Systems Improvement), 20081 [17]

Yes

BRCA1/2, CS, LFS, others3

General population

No

Yes

Yes

Yes

Management of Early Breast Cancer (New Zealand Guidelines Group), 20082 [18]

Yes

BRCA1/2, CS, LFS other 3

General population

Yes

Yes

Yes

Yes

Guidelines for Breast Screening with MRI as an Adjunct to Mammography (American Cancer Society), 20071 [19]

Yes

BRCA1/2, CS, LFS

General population

Yes

Yes

No

Yes

Risk Assessment and Genetic Counseling for Hereditary Breast and Ovarian Cancer: Recommendations (National Society of Genetic Counselors), 20071 [20]

No

BRCA1/2, CS, LFS, other3

General Population

Yes

Yes

Yes

Yes

Adult Preventive Health Care: Cancer Screening (University of Michigan), 20071 [21]

No

BRCA1/2

General population

No

No

No

Yes

The Early Detection of Breast Cancer (Towards Optimized Practice Alberta), 20072 [22]

Yes

BRCA1/2

General population

Yes

Yes

Yes

Yes

Familial breast cancer + Update (NHS), 20062 [23,24]

Yes

BRCA1/2, LFS

General population

Yes

Yes

Yes

Yes

Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Recommendation Statement (U.S. Preventive Services Task Force), 20042 [25]

Yes

BRCA1/2

General population

Yes

Yes

Yes

No

Management of Breast Cancer in Women (Scottish Intercollegiate Guidelines Group), 20042 [26]

Yes

BRCA1/2

General population

Yes

Yes

Yes

Yes

Guidelines for Breast Cancer Screening (American Cancer Society), 20031 [27]

Yes

BRCA1/2, CS, LFS

General population

Yes

Yes

Yes

Yes


Abbreviations: CS, Cowden syndrome; LFS, Li-Fraumeni syndrome

1Independent body/no endorsement.

2National/state endorsement.

3Other syndromes: Bannayan-Riley-Ruvalcaba syndrome, Peutz-Jeghers syndrome, hereditary diffuse gastric cancer and ataxia telangectasia.

Simone et al. BMC Medicine 2012 10:143   doi:10.1186/1741-7015-10-143

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