IL-22 serum concentrations are elevated in patients with liver cirrhosis (n = 120) compared with healthy individuals (n = 40). Dots indicate IL-22 serum levels in individual patients. The straight horizontal line indicates the mean. The dotted horizontal line indicates the upper limit of normal for IL-22 of 18 pg/ml. Error bars indicate the standard deviation. Comparison between the two groups was performed using the Mann Whitney U-test.
Kronenberger et al. BMC Medicine 2012 10:102 doi:10.1186/1741-7015-10-102