Toward a comprehensive language for biological systems
Department of Computational and Sytems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260 USA
BMC Biology 2011, 9:68 doi:10.1186/1741-7007-9-68Published: 17 October 2011
Rule-based modeling has become a powerful approach for modeling intracellular networks, which are characterized by rich molecular diversity. Truly comprehensive models of cell behavior, however, must address spatial complexity at both the intracellular level and at the level of interacting populations of cells, and will require richer modeling languages and tools. A recent paper in BMC Systems Biology represents a signifcant step toward the development of a unified modeling language and software platform for the development of multi-level, multiscale biological models.