Mobile DNA transposition in somatic cells
Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
BMC Biology 2011, 9:62 doi:10.1186/1741-7007-9-62Published: 29 September 2011
It had been long assumed that almost all insertions of mobile DNA elements occurred during germ-cell development rather than in somatic-cell development, but solid evidence for transposition in somatic cells is now accumulating. To add to this evidence, a recent paper in Mobile DNA reports the somatic transposition of a site-specific retrotransposon, R2, into its insertion site in 28S ribosomal DNA in Drosophila embryos.