Email updates

Keep up to date with the latest news and content from BMC Biology and BioMed Central.

Journal App

google play app store
Open Access Methodology article

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on 13C mass isotopologue profiles under non-steady-state conditions

Hunter NB Moseley12, Andrew N Lane13, Alex C Belshoff4, Richard M Higashi12 and Teresa WM Fan124*

Author Affiliations

1 Department of Chemistry and Center for Regulatory & Environmental Analytical Metabolomics (CREAM), University of Louisville, Louisville, KY 40292, USA

2 Structural Biology Program, JG Brown Cancer Center, University of Louisville, Louisville, KY 40292, USA

3 Department of Medicine, Clinical Translational Research Building, Louisville KY 40202, USA

4 Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202, USA

For all author emails, please log on.

BMC Biology 2011, 9:37  doi:10.1186/1741-7007-9-37

Published: 31 May 2011

Additional files

Additional file 1:

Supplemental figures and table. Figure S1: metabolite quantification in the medium: consumption and excretion. Figure S2: 1H-13C heteronuclear single quantum coherence (HSQC)-total correlation spectroscopy (TOCSY) of LN3 cells. Table S1: list of models of 13C incorporation into the biochemical units of UDP-N-acetyl-D-glucosamine (UDP-GlcNAc).

Format: DOC Size: 521KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data