Additional file 1.
Figure S1. Mutant rpn1 alleles derived from both the RY2H screen and rational mutagenesis display genetic interactions with mutations in genes that encode ubiquitin receptors intrinsic to the proteasome. Five-fold serial dilutions of cells were plated onto the indicated media. The rpn1 mutants (rpn1*) were plasmid shuffled into an rpn1Δ strain containing either no additional mutations (A) or rpn13Δ (B). AZC refers to 5 mM of the proline analog l-azetidine-2-carboxylic acid (AZC). In panel B, mutations derived from the RY2H screen are indicated with a red box.
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Gomez et al. BMC Biology 2011 9:33 doi:10.1186/1741-7007-9-33