cEPOR TG mice show increased impulsivity and reduced behavioral control under conditions of high cognitive challenge. (A) cEPOR TG mice were more distractible in trials comprising low frequency stimulus presentations (longer inter-trial interval) and (B) more impulsive in sessions including an irrelevant auditory distracter. (C) Additional evaluation of these phenomena using the marble burying test confirmed the impulsive phenotype. For all figures WT n = 9; TG n = 7, except (C): WT n = 18; TG n = 12; mean ± SEM presented.
Sargin et al. BMC Biology 2011 9:27 doi:10.1186/1741-7007-9-27