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Screening for genes that wire the cerebral cortex

Ludmilla Lokmane123 and Sonia Garel123*

Author Affiliations

1 Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, 46 rue d'Ulm, 75230 Paris cedex 05, France

2 INSERM, U1024, Avenir Team, 46 rue d'Ulm, 75230 Paris cedex 05, France

3 CNRS, UMR 8197, 46 rue d'Ulm, 75230 Paris cedex 05, France

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BMC Biology 2011, 9:1  doi:10.1186/1741-7007-9-1

Published: 7 January 2011

Abstract

Thalamocortical projections convey visual, somatosensory and auditory information to the cerebral cortex. A recent report in Neural Development shows how a forward genetic screen has enabled the identification of novel mutations affecting specific decision points of thalamocortical axon pathfinding.

See research article: http://www.neuraldevelopment.com/content/6/1/3/abstract webcite