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Mitochondrial dynamics: quantifying mitochondrial fusion in vitro

Alexis Jourdain and Jean-Claude Martinou*

Author affiliations

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland

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Citation and License

BMC Biology 2010, 8:99  doi:10.1186/1741-7007-8-99

Published: 26 July 2010

Abstract

Mitochondrial fusion is an essential process for preserving the integrity and stability of mitochondrial DNA; however, regulation of this process remains largely mysterious. In this issue of BMC Biology, Schauss and colleagues describe a simple, reliable, and robust novel assay that allows fusion of mammalian mitochondria to be quantified in vitro.

See research article: http://biomedcentral.com/1741-7007/8/100 webcite