The dmfrn gene is required for Drosophila male fertility and mitochondrial morphogenesis. (a, c) Wild-type and (b, d-e) dmfrn elongating spermatids as visualized by phase-contrast microscopy (a, b) and transmission electron microscopy (c-e). Arrows in (a, b) indicate the elongating flagellum in (a) wild-type, and (b) abnormally bunched mitochondria in dmfrn elongating cells. The arrow in (c) indicates paracrystalline material of the wild-type major mitochondrial derivative adjacent to the pinwheel structure of the flagellar axoneme. (d) The arrow points to a dmfrn mitochondrial derivative devoid of any paracrystalline material. Some mutant dmfrn spermatids in (e) show aberrant paracrystalline material distribution in both mitochondrial derivatives. Figure adapted from .
Hales BMC Biology 2010 8:79 doi:10.1186/1741-7007-8-79