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Open Access Commentary

Transcriptomics and disease vector control

John Vontas1*, Hilary Ranson2 and Luke Alphey34

Author Affiliations

1 Laboratory of Molecular Entomology, Faculty of Biotechnology and Applied Biology, Department of Biology, University of Crete, Heraklio, 71409, Greece

2 Vector Group, Liverpool School of Tropical Medicine, Liverpool, L35QA, UK

3 Oxitec Ltd, 71 Milton Park, Oxford OX14 4RX, UK

4 Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 2PS, UK

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BMC Biology 2010, 8:52  doi:10.1186/1741-7007-8-52

Published: 7 May 2010

Abstract

Next-generation sequencing can be used to compare transcriptomes under different conditions. A study in BMC Genomics applies this approach to investigating the effects of exposure to a range of xenobiotics on changes in gene expression in the larvae of Aedes aegypti, the mosquito vector of dengue fever.

See research article http://www.biomedcentral.com/1471-2164/11/216 webcite