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Open Access Highly Accessed Commentary

A central role for p38 MAPK in the early transcriptional response to stress

Alan J Whitmarsh

Author Affiliations

Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK

BMC Biology 2010, 8:47  doi:10.1186/1741-7007-8-47

Published: 27 April 2010


The mitogen-activated protein kinase p38 (p38 MAPK) is activated by a number of stresses. A recent study in BMC Genomics has uncovered the early transcriptional responses to three types of stress and has demonstrated a central role for p38 MAPK in mediating these responses.

See research article webcite