Table 4

Two-color FISH mapping results of putative TAP 2 and MHC Class I-containing clones.

MHC Class I

Mapping

TAP 2

Mapping

Colocalisation


TGAC-102M22*

1 micro

TGAC-167E04*

1 micro

No

TGAC-102M22*

1 micro

TGAC-86I22*

1 micro

No

TGAC-15A11

1 micro

TGAC-95I13

centromere macro

No

TGAC-181L18

1 micro

TGAC-53B12

Z

No

TGAC-12A09

micros, W

TGAC-14G17

1 micro and W

Yes

TGAC-250C06

micros

TGAC-139M05

1 micro

No

TGAC-252P06

1 micro

TGAC-249G24

1 micro

No


* Clones sequenced in this study

Most clones mapped to a single microchromosome (1 micro) where as some showed non specific binding to multiple microchromosomes (micros). A few clones mapped to sex chromosomes (Z and W), and one mapped to the centromeric region of a macrochromosome (macro). In only one cases did TAP2 and Class I clones colocalise, and that was on the W chromosome.

Balakrishnan et al. BMC Biology 2010 8:29   doi:10.1186/1741-7007-8-29

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