Figure 7.

Evolutionary positions of bacterial species with proline-containing Bridge Helices. The evolutionary relationship between three bacterial species with proline-containing Bridge Helices is shown on a rooted phylogenetic tree calculated using maximum-likelihood methods from a concatenation of representative protein sequences [63]. The three species occupy widely divergent branches, strongly suggesting that the proline substitutions evolved independently, rather than were derived from a recently shared ancestor.

Weinzierl BMC Biology 2010 8:134   doi:10.1186/1741-7007-8-134
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