Table 2

Zebrafish mutants used for the analysis of visuomotor function

Mutant

Alleles

Phenotype

Gene

Gene product

References


lakritz

lakth241c

Absence of RGCs and complete blindness; no known developmental defect outside the retina

atoh7 (ath5)

Atonal homolog 7

[66]

blumenkohl

blutc257z, blus391

Synaptic transmission defect in retinotectal axons; enlarged tectal receptive fields; reduced visual acuity

slc17a6b (vglut2a)

Vesicular glutamate transporter 2a

[16]

belladonna

beltv42, bels385, belb700

Incomplete crossing of retinal axons, reversed eye movements, 'looping' swim behavior

lhx2b

LIM-domain homeobox factor 2b

[67,93,94]

double indemnity

didys390, didys552

Reversible depletion of saccadic eye movements

scn1lab

Voltage-gated sodium channel NaV1.6

[60]


Nevin et al. BMC Biology 2010 8:126   doi:10.1186/1741-7007-8-126

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