Deletion of THOC5/FMIP is lethal in adult mice. Three day- (n = 25) (A) and nine-week-old (n = 7) (B) mice were injected with 50, and 500 μg of poly (I:C), respectively. Injection was performed i.p. three times at two to three day intervals. (arrows: poly (I:C) injection).
Mancini et al. BMC Biology 2010 8:1 doi:10.1186/1741-7007-8-1