BMC Biology

official impact factor 5.20

Open Access Research article

Ontogeny and phylogeny: molecular signatures of selection, constraint, and temporal pleiotropy in the development of Drosophila

Carlo G Artieri, Wilfried Haerty and Rama S Singh*

BMC Biology 2009, 7:42 doi:10.1186/1741-7007-7-42

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The odds of duplicate gene persistence after polyploidization

Frédéric JJ Chain, Jonathan Dushoff, Ben J Evans BMC Genomics 2011, 12:599 (12 December 2011)

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Comparative embryology without a microscope: using genomic approaches to understand the evolution of development

David A Garfield, Gregory A Wray Journal of Biology 2009, 8:65 (21 July 2009)

The early stages of development are generally very highly conserved. Garfield and Wray discuss recent genome-scale studies published in BMC Biology and aimed at testing three theories of how selection acts on early embryos.