Function of 2A peptide in various adult tissues. Sections through the heart (A, A'), lung (B, B'), liver (C, C'), kidney (D, D') and intestine (E, E') of adult CAG-TAG1 and CAG-TAG2 transgenic mice. The enhanced green fluorescent protein signal is depicted in green and TdTomato signal is depicted in magenta. No overlap of the H2B-GFP and Myr-TdTomato signal is seen, demonstrating efficient functioning of the 2A peptide. The scale bar in (A) represents 20 μm and is applicable to all panels.
Trichas et al. BMC Biology 2008 6:40 doi:10.1186/1741-7007-6-40