Figure 5.

DHA and EPA increase the amounts of PGE₂ in ScGT1 cells. (A) The amounts of PGE₂ produced by untreated ScGT1 cells (□) or by ScGT1 cells treated for 24 hours with 1 μM PUFA as shown (■). Values shown are the mean average amounts of PGE₂ (pg/ml) ± SD, n = 9. # = PGE₂ content significantly higher than that of control cells. (B) The amounts PGE₂ (pg/ml) in ScGT1 cells treated for 24 hours with different concentrations of DHA or EPA were plotted against the amounts of PrP^Sc (ng/ml) in ScGT1 cells treated for 7 days with the same concentrations of DHA (●) or EPA (○).