DHA and EPA increase the amounts of PGE2 in ScGT1 cells. (A) The amounts of PGE2 produced by untreated ScGT1 cells (□) or by ScGT1 cells treated for 24 hours with 1 μM PUFA as shown (■). Values shown are the mean average amounts of PGE2 (pg/ml) ± SD, n = 9. # = PGE2 content significantly higher than that of control cells. (B) The amounts PGE2 (pg/ml) in ScGT1 cells treated for 24 hours with different concentrations of DHA or EPA were plotted against the amounts of PrPSc (ng/ml) in ScGT1 cells treated for 7 days with the same concentrations of DHA (●) or EPA (○).
Bate et al. BMC Biology 2008 6:39 doi:10.1186/1741-7007-6-39