Table 2 |
||||||||
|
Neutral evolution robustness and mutation data. Each row represents a different generation,
T. NA indicates that no measurement was made. The 〈mnt〉 and 〈maa〉 are the average number of nucleotide mutations and nonsynonymous mutations, respectively.
Numbers in parentheses are total counts over the total samples. Subscripts indicate
the population type: U for unselected, P for polymorphic, and M for monomorphic. For the unselected and monomorphic populations, numbers represent
averages of all replicates. For the polymorphic population, numbers are for a random
sample of functional mutants. 〈 |
||||||||
|
T |
〈mnt〉U |
〈maa〉U |
〈mnt〉P |
〈maa〉P |
〈mnt〉M |
〈maa〉M |
〈 |
〈 |
|
|
||||||||
|
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0.48 (210/435) |
0.48 (210/435) |
|
1 |
NA |
NA |
NA |
NA |
0.1 (3/22) |
0.3 (6/22) |
0.48 (208/435) |
NA |
|
2 |
NA |
NA |
NA |
NA |
0.4 (9/22) |
0.8 (17/22) |
0.49 (215/435) |
NA |
|
3 |
5.0 (20/4) |
3.5 (14/4) |
2.7 (27/10) |
1.4 (14/10) |
1.0 (23/22) |
0.4 (9/22) |
0.49 (215/435) |
NA |
|
4 |
NA |
NA |
NA |
NA |
1.5 (32/22) |
0.7 (15/22) |
0.48 (208/435) |
NA |
|
5 |
NA |
NA |
NA |
NA |
2.2 (48/22) |
1.1 (25/22) |
0.45 (197/435) |
0.43 (185/435) |
|
6 |
9.8 (39/4) |
7.5 (30/4) |
5.5 (55/10) |
2.1 (21/10) |
2.6 (58/22) |
1.4 (31/22) |
0.46 (198/435) |
NA |
|
7 |
NA |
NA |
NA |
NA |
3.1 (69/22) |
1.8 (39/22) |
0.52 (227/435) |
NA |
|
8 |
NA |
NA |
NA |
NA |
3.4 (74/22) |
1.8 (40/22) |
0.46 (200/435) |
NA |
|
9 |
13.0 (52/4) |
10.3 (41/4) |
6.7 (61/9) |
3.1 (28/9) |
3.7 (82/22) |
2.1 (46/22) |
0.47 (203/435) |
NA |
|
10 |
NA |
NA |
NA |
NA |
4.2 (92/22) |
2.4 (52/22) |
0.46 (199/435) |
0.40 (175/435) |
|
11 |
NA |
NA |
NA |
NA |
4.6 (102/22) |
2.5 (56/22) |
0.48 (207/435) |
NA |
|
12 |
16.8 (67/4) |
12.5 (50/4) |
7.8 (70/9) |
3.3 (30/9) |
4.9 (107/22) |
2.6 (58/22) |
0.52 (228/435) |
NA |
|
13 |
NA |
NA |
NA |
NA |
5.0 (110/22) |
2.7 (60/22) |
0.52 (227/435) |
NA |
|
14 |
NA |
NA |
NA |
NA |
5.3 (116/22) |
2.9 (64/22) |
0.50 (216/435) |
NA |
|
15 |
NA |
NA |
10.3 (227/22) |
3.8 (83/22) |
5.6 (123/22) |
3.0 (67/22) |
0.50 (219/435) |
0.39 (171/435) |
|
16 |
NA |
NA |
NA |
NA |
5.8 (127/22) |
3.0 (67/22) |
NA |
NA |
|
17 |
NA |
NA |
NA |
NA |
6.0 (133/22) |
3.1 (69/22) |
NA |
NA |
|
18 |
NA |
NA |
NA |
NA |
6.3 (137/22) |
3.2 (71/22) |
NA |
NA |
|
19 |
NA |
NA |
NA |
NA |
6.3 (138/22) |
3.3 (72/22) |
NA |
NA |
|
20 |
NA |
NA |
NA |
NA |
6.6 (145/22) |
3.4 (75/22) |
NA |
0.37 (160/435) |
|
21 |
NA |
NA |
NA |
NA |
6.9 (152/22) |
3.6 (79/22) |
NA |
NA |
|
22 |
NA |
NA |
NA |
NA |
7.1 (156/22) |
3.7 (81/22) |
NA |
NA |
|
23 |
NA |
NA |
NA |
NA |
7.2 (158/22) |
3.7 (81/22) |
NA |
NA |
|
24 |
NA |
NA |
NA |
NA |
7.3 (161/22) |
3.8 (83/22) |
NA |
NA |
|
25 |
NA |
NA |
NA |
NA |
7.7 (169/22) |
4.0 (87/22) |
NA |
0.39 (169/435) |
|
|
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|
Bloom et al. BMC Biology 2007 5:29 doi:10.1186/1741-7007-5-29 |
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