Evolution favors protein mutational robustness in sufficiently large populations

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Jesse D Bloom^*, Zhongyi Lu, David Chen, Alpan Raval, Ophelia S Venturelli and Frances H Arnold^*

* Corresponding authors: Jesse D Bloom jesse.bloom@gmail.com - Frances H Arnold frances@cheme.caltech.edu

BMC Biology 2007, 5:29 doi:10.1186/1741-7007-5-29