Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA

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Research article

Bora E Baysal¹^,2 , Elizabeth C Lawrence² and Robert E Ferrell²

¹Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA

²Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA

author email corresponding author email

BMC Biology 2007, 5:12doi:10.1186/1741-7007-5-12


Published:	21 March 2007

Additional file 1:

Additional Table 1 – S DH subunit gene variants

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Additional file 2:

Additional Table 2 – Sequence variants and fixed differences in chimpanzee SDHA

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Additional file 3:

Additional Table 3 – Locus-by-locus HKA tests of SDHA versus neutrally evolving loci

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Additional file 4:

Additional Table 4 – Haplotype structures of SDHB, SDHC, and SDHD

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Additional file 5:

Additional Table 5 – PCR oligonucleotide primers and the amplicon sizes for SDHA, SDHB, SDHC, and SDHD exons

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