Expression of mammalian GPCRs in C. elegans generates novel behavioural responses to human ligands

doi:10.1186/1741-7007-4-22

BMC Biology

Volume 4

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Teng MS
Dekkers MP
Ng BL
Rademakers S
Jansen G
Fraser AG
McCafferty J

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Ng BL
Rademakers S
Jansen G
Fraser AG
McCafferty J
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Research article

Expression of mammalian GPCRs in C. elegans generates novel behavioural responses to human ligands

Michelle S Teng¹ , Martijn PJ Dekkers² , Bee Ling Ng¹ , Suzanne Rademakers¹ , Gert Jansen² , Andrew G Fraser¹ and John McCafferty¹

¹Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK

²MGC Department of Cell Biology and Genetics, Centre for Biomedical Genetics, Erasmus MC, Rotterdam, The Netherlands

author email corresponding author email

BMC Biology 2006, 4:22doi:10.1186/1741-7007-4-22


Published:	20 July 2006

Additional files

Additional File 1:

Teng et. al. 34 kb Method for flow sorting and figure legend for additional file 2.

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Additional File 2:

Teng et. al. 4.2 MB Flow sorting table and figure. Summary table for MoFlo sorting conditions and confocal images of sorted transgenic populations

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Additional File 3:

Teng et. al. 25 kb Comparison of avoidance indices of population vs single animal avoidance assay (dry drop test)

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