Compensation by tumor suppressor genes during retinal development in mice and humans

doi:10.1186/1741-7007-4-14

BMC Biology

Volume 4

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Research article

Compensation by tumor suppressor genes during retinal development in mice and humans

Stacy L Donovan¹^* , Brett Schweers¹^* , Rodrigo Martins¹ , Dianna Johnson² and Michael A Dyer¹^,2

¹Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA

²Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA

author email corresponding author email* Contributed equally

BMC Biology 2006, 4:14doi:10.1186/1741-7007-4-14


Published:	3 May 2006

Additional files

Additional file 1:

Expression of the Rb, p107 and p130 during the cell cycle in retinal progenitor cells.

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Additional file 2:

Human fetal retinal explant cultures.

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Additional file 3:

Effects of acute inactivation of Rb in the developing retina.

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Additional file 4:

Acute inactivation of p107 in the Rb-deficient retinae during development.

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Additional file 5:

Expression of Proliferation and Differentiation Markers in P0 Retinae Lacking Rb and/or p107.

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Additional file 6:

Expression of Proliferation and Differentiation Markers in P6 Retinae Lacking Rb and/or p107.

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Additional file 7:

Expression of Proliferation and Differentiation Markers in P12 Retinae Lacking Rb and/or p107.

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Additional file 8:

Expression of Proliferation and Differentiation Markers in P30 Retinae Lacking Rb and/or p107.

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Additional file 9:

Clone composition and distribution from in vivo lineage analysis.

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Additional file 10:

Antibodies used for immunofluorescence on adult tissue.

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