Additional File 3.

(QuickTime format) FZ-2 morphant movie. Figure 1I–N panels were taken from this movie at the indicated time points. As also noted in non-injected insulin:GFP transgenic embryos, GFP-positive cells are first observed around the 14 somite stage as bilateral patches, and these cells divide normally in fz-2 MO-injected embryos. However, the uniform migration towards the posterior observed in the non-injected transgenic embryo is not observed in fz-2 MO-injected embryos. Instead, the polarity of cell migration is entirely lost, with no net movement along the anterior-posterior axis observed for these cells (see text).

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Kim et al. BMC Biology 2005 3:23   doi:10.1186/1741-7007-3-23