Open Access Highly Accessed Research article

Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization

Emmanuel G Reynaud1*, Miguel A Andrade2, Fabien Bonneau3, Thi Bach Nga Ly1, Michael Knop1, Klaus Scheffzek3 and Rainer Pepperkok1*

Author Affiliations

1 Cell Biology and Cell Biophysics Programme, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany

2 Ontario Genomics Innovation Centre, Ottawa Health Research Institute, 501 Smyth, Ottawa, ON K1H 8L6, Canada

3 Structural and Computational Programme, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany

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BMC Biology 2005, 3:21  doi:10.1186/1741-7007-3-21

Published: 7 October 2005

Additional files

Additional File 1:

Complete Phylogenetic Tree of the YRG family. A multiple alignment of sequences of the YqeH, YjeQ, EngA, and YlqF families. The alignment was produced using ClustalW followed by manual editing [16]. The tree was generated from the alignment using MrBayes v3 [45] (The root of the tree is the one given by the MrBayes output.

Format: EPS Size: 9.4MB Download file

Open Data

Additional File 2:

The YRG family members. The table compiles all the data collected from several datasets available for all the YRG members known so far.

Format: EPS Size: 9.3MB Download file

Open Data