Table 1

Abbreviations used to designate substrate specificities of tyrA/TyrA homologs

Abbreviationa


Gene
Gene Product
Description of specificityb

tyrAx
TyrAx
Specificity for cyclohexadienyl substrate is unknown
tyrAc
TyrAc
Broad-specificity cyclohexadienyl dehydrogenase (CDH)
tyrAp
TyrAp
Narrow-specificity prephenate dehydrogenase (PDH)
TyrAc_Δ
TyrAc_Δ
Broad-specificity cyclohexadienyl dehydrogenase having catalytic-core indels in correlation with an extra-core extension
tyrAa
TyrAa
Narrow-specificity arogenate dehydrogenase (ADH)
NADtyrAa
NADTyrAa
TyrA homolog is AGN-specific and NAD+-specific
NADPtyrAa
NADPTyrAa
TyrA homolog is AGN-specific and NADP+-specific
NAD(P)tyrAa
NAD(P)TyrAa
TyrA homolog is AGN-specific but utilizes either NAD+ or NADP+
xtyrAx
xTyrAx
Specificity for both the cyclohexadienyl and pyridine nucleotide substrates is unknown

aAbbreviations in the upper-table (upper 5 rows) indicate the specificities for the cyclohexadienyl substrate. Abbreviations in the lower-table (lower 4 rows) indicate specificities for both cyclohexadienyl (right subscripts) and pyridine nucleotide substrates (left subscripts). Combinations not shown can be deduced from the examples given, e.g., a TyrA homolog specific for prephenate and NAD+ would be designated NADTyrAp.

bThe abbreviations CDH, PDH, and ADH (shown parenthetically) have been used frequently in the literature.

Song et al. BMC Biology 2005 3:13   doi:10.1186/1741-7007-3-13